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Recombinant Human Metalloendopeptidase OMA1, mitochondrial (OMA1) (Active)

Recombinant Human Metalloendopeptidase OMA1, mitochondrial (OMA1) (Active)

ArtNr	BM-RPC27027-100ug
Hersteller	Biomatik
Menge	100ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Metalloprotease-related protein 1
Similar products	Metalloprotease-related protein 1
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Gene Name	OMA1
Alternative Names	Metalloprotease-related protein 1
Uniprot	Q96E52
Source	in vitro E.coli expression system
Expression Region	14-524aa
AA Sequence	HVFFRFNSLSNWRKCNTLASTSRGCHQVQVNHIVN KYQGLGVNQCDRWSFLPGNFHFYSTFNNKRTGGLS STKSKEIWRITSKCTVWNDAFSRQLLIKEVTAVPS LSVLHPLSPASIRAIRNFHTSPRFQAAPVPLLLMI LKPVQKLFAIIVGRGIRKWWQALPPNKKEVVKENI RKNKWKLFLGLSSFGLLFVVFYFTHLEVSPITGRS KLLLLGKEQFRLLSELEYEAWMEEFKNDMLTEKDA RYLAVKEVLCHLIECNKDVPGISQINWVIHVVDSP IINAFVLPNGQMFVFTGFLNSVTDIHQLSFLLGHE IAHAVLGHAAEKAGMVHLLDFLGMIFLTMIWAICP RDSLALLCQWIQSKLQEYMFNRPYSRKLEAEADKI GLLLAAKACADIRASSVFWQQMEFVDSLHGQPKMP EWLSTHPSHGNRVEYLDRLIPQALKIREMCNCPPL SNPDPRLLFKLSTKHFLEESEKEDLNITKKQKMDT LPIQKQEQIPLTYIVEKRTGS
Sequence Info	Full Length
Tag Info	N-terminal 6xHis-SUMO-tagged
Theoretical MW	74.7 kDa
Purity	>90% as determined by SDS-PAGE.
Storage Buffer	Lyophilized from 20 mM Tris-HCl, 0.15 M NaCl, 0.05% FOS12, 6% Trehalose, pH 8.0
Endotoxin Level	Not tested
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized OMA1 at 5 ug/ml can bind human BZW2, the EC50 of human BZM2 is 45.42-72.22 ug/ml.
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100ug

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Lieferung vsl. bis 09.10.2025