Chicken polyclonal antibody to mouse C-Reactive protein (210-225): Affinity purified

C-reactive protein has several roles associated with host defence such as, promoting agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. COFACTOR: Binds 2 calcium ions per subunit. C-reactive protein exists as a homopentamer. There are 2 alternatively spliced isoforms. C-reactive protein is found in plasma and its concentration increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6.

Short term storage at 2-8AC for one week. At -20AC as an undiluted liquid for up to 12 months.

A peptide from the C-terminus of mouse C-reactive protein (210-225 aa).

Chicken