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Mouse monoclonal antibody to Glyceraldehyde 3-Phosphate Dehydrogenase [1D4]

ArtNr M-1376-250
Hersteller Biosensis
Menge 250ul
Kategorie
Typ Antibody Monoclonal
Applikationen WB, ICC
Clon 1D4
Specific against other
Host Mouse
Isotype IgM
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Similar products GAPDH, GAPD, Glyceraldehyde-3-phosphate dehydrogenase, G3PDH, GPDH
Lieferbar
Sub category
Cancer
products_extra_fields_value
Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) is a metabolic enzyme responsible for catalyzing one step in the glycolytic pathway, the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate. GAPDH may have other roles in the activation of transcription and in the regulation of apoptosis as well as Alzheimer's disease and Huntington's disease. The immunogen used to raise this particular antibody was extensively purified pig GAPDH. This antibody can be used as a loading control for western blotting experiments, allowing comparison between the level of this protein and others in a cell or tissue.
products_quantity
200
storage
After reconstitution of lyophilised antibody, aliquot and store at -20AC for a higher stability. Avoid freeze-thaw cycles.
formulation
Lyophilised with 5% trehalose
immunogen
Purified pig GAPDH
crossreactivity
Human, Rat, Mouse, Bovine, Porcine, Chicken
conality
Mouse
specificity
The specificity of this antibody has been confirmed by WB.
reconstitution
Reconstitute in sterile distilled water. Centrifuge to remove any insoluble material.
specificreferences
1. Fortun J. et al (2003) Emerging role for autophagy in the removal of aggresomes in Schwann cells. J Neurosci. 2003 Nov 19, 23(33):10672-80.
2. Felitsyn N. et al (2008) The heme precursor delta-aminolevulinate blocks peripheral myelin formation. J Neurochem. 2008 Sep, 106(5):2068-79.
3. Iskandar M. et al (2005) Copper chaperone for Cu/Zn superoxide dismutase is a sensitive biomarker of mild copper deficiency induced by moderately high intakes of zinc. Nutr J. 2005 Nov 24, 4:35.
4. Bizzozero O.A. et al (2009) Identification of major S-nitrosylated proteins in murine experimental autoimmune encephalomyelitis. J Neurosci Res. 2009 Oct, 87(13):2881-9.
5. Madorsky I. et al (2009) Intermittent fasting alleviates the neuropathic phenotype in a mouse model of Charcot-Marie-Tooth disease. Neurobiol Dis. 2009 Apr, 34(1):146-54.
6. Bertinato J. et al (2010) Decreased Erythrocyte CCS Content is a Biomarker of Copper Overload in Rats. Int J Mol Sci. 2010 Jul 2, 11(7):2624-35.
7. Rangaraju S. et al (2008) Pharmacological induction of the heat shock response improves myelination in a neuropathic model. Neurobiol Dis. 2008 Oct, 32(1):105-15.
8. Rangaraju S. et al (2009) Molecular architecture of myelinated peripheral nerves is supported by calorie restriction with aging. Aging Cell. 2009 Apr, 8(2):178-91.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250ul
Lieferbar: In stock
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