Mouse monoclonal antibody to Protein S100-beta [SA-12]: IgG

Protein S100 beta belongs to the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. The 2 subunits of S100 protein are the products of separate genes. The beta subunit is present in all S100 positive cells and tumours whereas the alpha subunit is detectable only in specific tissues such as heart, skeletal muscle and brain. The S100 protein is a homodimer composed of two alpha subunits (S100a) or two beta subunits (S100b) or as a heterodimer with one alpha and beta subunit (S100ab or S100ao). This antibody reacts specifically with the beta subunit.

At least 12 months after purchase at 2 - 4AC (lyophilized formulations).After reconstitution, aliquot and store at -20AC for a higher stability. Avoid freeze-thaw cycles.

Lyophilized from 1.2% sodium acetate, 2mg BSA, 0.01mg NaN3

Human, mouse, rat

The specificity of this antibody has been confirmed by WB and IHC against the antigen.