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Rabbit polyclonal antibody to BDNF (162-176): Affinity purified

ArtNr R-1004-100
Hersteller Biosensis
Menge 100ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products proBDNF, Brain-derived neurotrophic factor, Abrineurin
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Sub category
Neurotrophic Factors-Stem Cells
products_extra_fields_value
BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycaemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. Post translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.
products_quantity
200
storage
After reconstitution, aliquot and store at -20AC for a higher stability. Avoid freeze-thaw cycles.
purityisotype
Affinity purified on antigen column
formulation
Liquid (0.5ml). 50% glycerol, 0.9mg NaCl and 0.2mg Na2HPO4
immunogen
A peptide (GTVTVLEKVPVSKGQ) corresponding to amino acids 162-176 from human BDNF precursor.
crossreactivity
Human, mouse, rat, rabbit,
conality
Rabbit
specificity
The specificity of this antibody has been confirmed by WB against the antigen.
reconstitution
The liquid formulation should be diluted in PBS (pH 7.4).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ug
Lieferbar: In stock
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