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Rabbit antibody to PTH2 receptor (481-501): whole serum

ArtNr R-120-100
Hersteller Biosensis
Menge 100ul
Kategorie
Typ Antibody
Applikationen WB
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products Parathyroid hormone receptor, PTH2 receptor, Pthr2
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Sub category
Receptors & Channel Molecules-G-Protein Coupled Receptors
products_extra_fields_value
FUNCTION: This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by g proteins which activate adenylyl cyclase. PTHR2 may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTHR2 presence in neurons indicates that it may function as a neurotransmitter receptor. SUBUNIT: Binds to TIPF39/TIP39. SUBCELLULAR LOCATION: Membrane, multi-pass membrane protein. TISSUE SPECIFICITY: Abundantly expressed in brain, arterial and cardiac endothelium. Found as well in sperm, in the head of the epididymis. Lower expression is found in vascular smooth muscle, exocrine pancreas, testis and placenta. SIMILARITY: Belongs to the G-protein coupled receptor 2 family.
products_quantity
200
storage
After reconstitution keep aliquots at -20AC for a higher stability, and at 4AC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
purityisotype
Whole serum
formulation
Lyophilised
immunogen
A synthetic peptide (RQIDSHVTLPGYVWSSSEQDC) of rat Parathyroid hormone receptor protein (aa: 481-501) conjugated to KLH has been used as the immunogen.
crossreactivity
This antibody is known to react with rat Parathyroid hormone receptor.
conality
Rabbit
specificity
Specificity has been shown by western blot. A band of 63 kDa corresponding to the theoretical molecular weight of Parathyroid hormone receptor is easily detectable by WB. Absorption of the antiserum with the immunising peptide abolished the binding of the antibody to the target hence detectability of the band.
reconstitution
Reconstitute in 100 Aul of sterile water. Centrifuge to remove any insoluble material.

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Menge: 100ul
Lieferbar: In stock
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