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Alpha synuclein control peptide (116-131)

Alpha synuclein control peptide (116-131)

ArtNr	PE-1606-100
Hersteller	Biosensis
Menge	100ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Peptides & Proteins Peptides
Typ	Peptides
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor
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products_extra_fields_value	Alpha synuclein is an abundant 140 amino acid neuronal protein, expressed primarily at presynaptic terminals in the central nervous system. Alpha synuclein has been associated with several neurodegenerative diseases. A point mutation in the gene coding for the alpha-synuclein protein was the first discovery linking this protein to a rare familial form of Parkinson's disease (PD). Subsequently, other mutations in the alpha-synuclein gene have been identified in familial PD. The aggregated proteinaceous inclusions called Lewy bodies found in PD and cortical Lewy body dementia (LBD) were discovered to be predominantly alpha-synuclein. Aberrant aggregation of alpha-synuclein has been detected in an increasing number of neurodegenerative diseases, collectively known as synucleopathies. Alpha-synuclein exists physiologically in both soluble and membrane-bound states, in unstructured and alpha-helical conformations, respectively. The physiological function of alpha-synuclein appears to require its translocation between these subcellular compartments and interconversion between the 2 conformations. Abnormal processing of alpha-synuclein is predicted to lead to pathological changes in its binding properties and function.
products_quantity	199
storage	After reconstitution keep at -20AC. Avoid repetitive freeze/thaw cycles.
purityisotype	Crude
formulation	Lyophilized
immunogen	A synthetic peptide (CMPVDPDNEAYEMPSEE) of human alpha synuclein protein (aa: 116-131).
reconstitution	This peptide is soluble in PBS and water.

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Menge: 100ug

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Lieferung vsl. bis 13.11.2025

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