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Human TrkB-Fc Chimera expressed in mammalian cells

Human TrkB-Fc Chimera expressed in mammalian cells

ArtNr	PE-1235-20
Hersteller	Biosensis
Menge	20ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Status Necrosis Adenocarcinoma Cytoskeleton Flow Cytometry Microfilaments By Organ Colorectal Cancer Thyroid Cancer
Typ	Proteins
Applikationen	FC
Specific against	other
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	Ntrk2, Trkb, BDNF/NT-3 growth factors receptor, GP145-TrkB/GP95-TrkB, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Trk-B, Tropomyosin-related kinase receptor, TrkB-Fc Chimera
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Sub category	Receptor Body Chimeras
products_extra_fields_value	Tyrosine Kinase Receptor B (TrkB) is a high affinity receptor for brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5. It also binds neurotrophin 3 (NT-3) with lower affinity. TrkB does not bind nerve growth factor (NGF). TrkB is involved in the development and/or maintenance of the nervous system and is widely expressed, predominantly in nervous tissue. TrkB is a heavily glycosylated type I transmembrane protein. The TrkB-Fc chimera contains 13 potential N-linked glycosylation sites.
products_quantity	200
storage	Lyophilized products should be stored at 2 to 8AC. Following reconstitution, short-term storage at 4AC is recommended and longer-term storage of aliquots at -18 to -20AC. Repeated freeze thawing is not recommended.
purityisotype	>95%, as determined by SDS-PAGE and visualized by silver stain.
formulation	The chimera consists of 20-40% carbohydrate by weight.
conality	Human - A DNA sequence encoding the signal peptide and extracellular domain of human TrkB (amino acids 1- 428) was fused to the Fc region of human IgG1 (amino acids 93-330). The chimeric protein was expressed in modified human 293 cells.
reconstitution	It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.

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