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Human Stem Cell Factor Receptor-Fc Chimera expressed in mammalian cells

Human Stem Cell Factor Receptor-Fc Chimera expressed in mammalian cells

ArtNr	PE-1244-50
Hersteller	Biosensis
Menge	50ug
Kategorie	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins By Organ Heart & Blood Cancer
Typ	Proteins
Specific against	other
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	SCFR, Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit, c-kit, CD117
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Sub category	Receptor Body Chimeras
products_extra_fields_value	Stem Cell Factor Receptor (SCFR) is a member of the receptor tyrosine kinase family. Binding of SCFR to its ligand Stem Cell Factor (PE-2008-5) induces receptor dimerization, autophosphorylation and signal transduction. SCFR is essential for the development of normal hematopoietic cells and plays an important role in the survival, proliferation and differentiation of mast cells, melanocytes and germ cells.
products_quantity	200
storage	Lyophilized products should be stored at 2 to 8AC. Following reconstitution short-term storage at 4AC is recommended, and longer-term storage of aliquots at -18 to -20AC. Repeated freeze thawing is not recommended.
purityisotype	>95%, as determined by SDS-PAGE and visualized by silver stain
formulation	The SCFR-Fc Chimera consists of 5-45% carbohydrate by weight. When reconstituted in 0.5 ml sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose.
conality	Human - A DNA sequence encoding the signal peptide and extracellular domain of human Stem Cell Factor Receptor (amino acids 1-520) was fused to the Fc region of human IgG1 (amino acids 93-330). The chimeric protein was expressed in modified human 293 cells.
reconstitution	It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.

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