Hersteller |
Bioworld Technology, Inc
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Applikationen |
WB, IHC |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
BS3485-50 |
Targets |
ACE |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Swiss-Prot |
P12821 |
Application all |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 |
Background |
Angiotensin-converting enzyme (ACE) is a carboxy-terminal dipeptidyl exo-peptidase that converts Angiotensin I to the potent vasopressive hormone, Angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically, late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in fluid/electrolyte homeostasis. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
ACE (F940) pAb detects endogenous levels of Angiotensin-converting enzyme protein. |
WB |
Western blot (WB) analysis of ACE (F940) pAb at 1:500 dilution Lane1:Hela cell lysate Lane2:PC12 cell lysate Lane3:Mouse kidney tissue lysate Lane4:Rat liver tissue lysate |
IHC |
Immunohistochemistry (IHC) analyzes of ACE (F940) pAb in paraffin-embedded human brain tissue. |
BiowMW |
Predicted band size:150KDa Observed band size:195KDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Angiotensin-converting enzyme, Short name=ACE, Dipeptidyl carboxypeptidase I, CD143, ACE1, DCP, DCP1, Angiotensin Converting Enzyme 1 |
Immunogen |
Synthetic peptide, corresponding to amino acids 920-950 of Human ACE. |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.