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Cytokeratin 13 (E282) polyclonal antibody

Cytokeratin 13 (E282) polyclonal antibody

Hersteller	Bioworld Technology, Inc
Kategorie	Neuroscience Neural Lineage Markers Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot Primary Antibodies Intermediate filaments
Typ	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Applikationen	WB, IHC
Menge	100ul
Host	Rabbit
ArtNr	BS3504-100
eClass 6.1	32160702
eClass 9.0	32160702
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Swiss-Prot	P13646
Application all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200
Background	Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	Cytokeratin 13 (E282) pAb detects endogenous levels of Cytokeratin 13 protein.
WB	Western blot (WB) analysis of Cytokeratin 13 (E282) pAb at 1:500 dilution Lane1:A549 cell lysate Lane2:H9C2 cell lysate
IHC	Immunohistochemistry (IHC) analyzes of Cytokeratin 13 (E282) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.
BiowMW	ca. 50 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Keratin, type I cytoskeletal 13, Cytokeratin-13, Cytokeratin 13, Cytokeratin13, Short name=CK-13, CK13, Keratin-13, Keratin13, Keratin 13, Short name=K13, KRT13
Immunogen	Synthetic peptide, corresponding to amino acids 250-300 of Human Cytokeratin 13.

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