Anti-Phospho-Fusin (S339) CXCR4 Antibody

Primary Antibodies

39746 MW

WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000

C-X-C chemokine receptor type 4

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

1 mg/ml

Receptor for the C-X-C chemokine CXCL12/SDF-1 that
transduces a signal by increasing intracellular calcium ion levels
and enhancing MAPK1/MAPK3 activation (PubMed:10452968,
PubMed:28978524, PubMed:18799424, PubMed:24912431). Involved in
the AKT signaling cascade (PubMed:24912431). Plays a role in
regulation of cell migration, e.g. during wound healing
(PubMed:28978524). Acts as a receptor for extracellular ubiquitin;
leading to enhanced intracellular calcium ions and reduced
cellular cAMP levels (PubMed:20228059). Binds bacterial
lipopolysaccharide (LPS) et mediates LPS-induced inflammatory
response, including TNF secretion by monocytes (PubMed:11276205).
Involved in hematopoiesis and in cardiac ventricular septum
formation. Also plays an essential role in vascularization of the
gastrointestinal tract, probably by regulating vascular branching
and/or remodeling processes in endothelial cells. Involved in
cerebellar development. In the CNS, could mediate hippocampal-
neuron survival (By similarity).

Boster Bio Anti-Phospho-Fusin (S339) CXCR4 Antibody catalog # A00031S339-1. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat, Monkey.

Boster Bio Anti-Phospho-Fusin (S339) CXCR4 Antibody catalog # A00031S339-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.