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Anti-Phospho-Bcl-2 (T74) Antibody

Anti-Phospho-Bcl-2 (T74) Antibody

ArtNr	BOS-A00040T74
Hersteller	Boster
Menge	100 ul
Kategorie	Oncology By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis Immunohistochemistry ELISA Immunofluorescence Autophagy By Organ Colorectal Cancer Testicular & Prostate Cancer Immunostaining
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Alias	Apoptosis regulator Bcl-2,BCL2
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	26266 MW
Clonality	Polyclonal
Application Details	IHC 1:100-1:300 ELISA 1:10000 IF 1:50-200
Gene Name	BCL2
Gene Full Name	Apoptosis regulator Bcl-2
Immunogen	Synthesized phospho-peptide around the phosphorylation site of human Bcl-2 (phospho Thr74)
Contents	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Protein Name	Apoptosis regulator Bcl-2
Protein Function	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Subcellular Localization	Mitochondrion outer membrane
Description	Boster Bio Anti-Phospho-Bcl-2 (T74) Antibody catalog # A00040T74. Tested in IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in a variety of tissues.
Short Description	Boster Bio Anti-Phospho-Bcl-2 (T74) Antibody catalog # A00040T74. Tested in ELISA, IHC applications. This antibody reacts with Human.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-A00040T74-datasheet.pdf

BOS-A00040T74-safety-datasheet.pdf