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Anti-Phospho-CD44 (S706) Antibody Europäischer Partner

ArtNr BOS-A00052S706
Hersteller Boster
Menge 100 ul
Kategorie
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Alias CD44 antigen,CDw44,Epican,Extracellular matrix receptor III,ECMR-III,GP90 lymphocyte homing/adhesion receptor,HUTCH-I,Heparan sulfate proteoglycan,Hermes antigen,Hyaluronate receptor,Phagocytic glycoprotein 1,PGP-1,Phagocytic glycoprotein I,PGP-I,CD44,CD44,LHR,MDU2,MDU3,MIC4
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight
81538 MW
Clonality
Polyclonal
Application Details
WB 1:500-1:2000
ELISA 1:20000
Gene Name
CD44
Gene Full Name
CD44 antigen
Immunogen
The antiserum was produced against synthesized peptide derived from human CD44 around the phosphorylation site of Ser706. AA range:681-730
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Protein Name
CD44 antigen
Protein Function
Receptor for hyaluronic acid (HA). Mediates cell-cell
and cell-matrix interactions through its affinity for HA, and
possibly also through its affinity for other ligands such as
osteopontin, collagens, and matrix metalloproteinases (MMPs).
Adhesion with HA plays an important role in cell migration, tumor
growth and progression. In cancer cells, may play an important
role in invadopodia formation. Also involved in lymphocyte
activation, recirculation and homing, and in hematopoiesis.
Altered expression or dysfunction causes numerous pathogenic
phenotypes. Great protein heterogeneity due to numerous
alternative splicing and post-translational modification events.
Receptor for LGALS9; the interaction enhances binding of SMAD3 to
the FOXP3 promoter, leading to up-regulation of FOXP3 expression
and increased induced regulatory T (iTreg) cell stability and
suppressive function (By similarity).
Subcellular Localization
Cell membrane
Description
Boster Bio Anti-Phospho-CD44 (S706) Antibody catalog # A00052S706. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Isoform 10 (epithelial isoform) is expressed
by cells of epithelium and highly expressed by carcinomas.
Expression is repressed in neuroblastoma cells.
Short Description
Boster Bio Anti-Phospho-CD44 (S706) Antibody catalog # A00052S706. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Manufacturer - Alias
CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, CD44, LHR, MDU2, MDU3, MIC4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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