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Anti-Smad2 (phospho-S467) Antibody

Anti-Smad2 (phospho-S467) Antibody

ArtNr	BOS-A00090S467
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Immunohistochemistry Western Blot Neurodegeneration Markers
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Mothers against decapentaplegic homolog 2,MAD homolog 2,Mothers against DPP homolog 2,JV18-1,Mad-related protein 2,hMAD-2,SMAD family member 2,SMAD 2,Smad2,hSMAD2,SMAD2,MADH2,MADR2
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	52306 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:1000 IHC: 1:50-1:200
Gene Name	SMAD2
Gene Full Name	Mothers against decapentaplegic homolog 2
Immunogen	Synthetic phosphopeptide derived from human Smad2 around the phosphorylation site of Serine 467.
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Mothers against decapentaplegic homolog 2
Protein Function	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Subcellular Localization	Cytoplasm
Description	Boster Bio Anti-Smad2 (phospho-S467) Antibody catalog # A00090S467. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta.

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BOS-A00090S467-datasheet.pdf

BOS-A00090S467-safety-datasheet.pdf