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Anti-Phospho-Smad2 (T220) Antibody

Anti-Phospho-Smad2 (T220) Antibody

ArtNr	BOS-A00090T220
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Immunohistochemistry Western Blot ELISA Immunofluorescence Immunostaining Neurodegeneration Markers
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Alias	Mothers against decapentaplegic homolog 2,MAD homolog 2,Mothers against DPP homolog 2,JV18-1,Mad-related protein 2,hMAD-2,SMAD family member 2,SMAD 2,Smad2,hSMAD2,SMAD2,MADH2,MADR2
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	52306 MW
Clonality	Polyclonal
Application Details	WB 1:500-2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:10000 WB 1:500-2000
Gene Name	SMAD2
Gene Full Name	Mothers against decapentaplegic homolog 2
Immunogen	The antiserum was produced against synthesized peptide derived from human Smad2 around the phosphorylation site of Thr220. AA range:186-235
Contents	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Protein Name	Mothers against decapentaplegic homolog 2
Protein Function	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Subcellular Localization	Cytoplasm
Description	Boster Bio Anti-Phospho-Smad2 (T220) Antibody catalog # A00090T220. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta.
Short Description	Boster Bio Anti-Phospho-Smad2 (T220) Antibody catalog # A00090T220. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-A00090T220-datasheet.pdf

BOS-A00090T220-safety-datasheet.pdf