Anti-Rac1/Cdc42 (Phospho-Ser71) Antibody

Primary Antibodies

21259 MW

WB: 1:500-1:1, 000
ICC: 1:50-1:200
IHC: 1:50-1:200

Cell division control protein 42 homolog

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Plasma membrane-associated small GTPase which cycles
between an active GTP-bound and an inactive GDP-bound state. In
active state binds to a variety of effector proteins to regulate
cellular responses. Involved in epithelial cell polarization
processes. Regulates the bipolar attachment of spindle
microtubules to kinetochores before chromosome congression in
metaphase. Plays a role in the extension and maintenance of the
formation of thin, actin-rich surface projections called
filopodia. Mediates CDC42-dependent cell migration. Required for
DOCK10-mediated spine formation in Purkinje cells and hippocampal
neurons. Facilitates filopodia formation upon DOCK11-activation
(By similarity). Also plays a role in phagocytosis through
organization of the F-actin cytoskeleton associated with forming
phagocytic cups.

Boster Bio Anti-Rac1/Cdc42 (Phospho-Ser71) Antibody catalog # A00119S71. Tested in WB, ICC/IF, IHC applications. This antibody reacts with Human.