Anti-Phospho-Bcl-x (T47) BCL2L1 Antibody

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Polyclonal

BCL2L1

The antiserum was produced against synthesized peptide derived from human BCL-XL around the phosphorylation site of Thr47. AA range:13-62

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Bcl-2-like protein 1

Isoform Bcl-X (L): Mitochondrion inner
membrane. Mitochondrion outer membrane
. Mitochondrion matrix. Cytoplasmic
vesicle, secretory vesicle, synaptic vesicle membrane
. Cytoplasm, cytosol. Cytoplasm,
cytoskeleton, microtubule organizing center, centrosome. Nucleus
membrane; Single-pass membrane protein
; Cytoplasmic side. After neuronal
stimulation, translocates from cytosol to synaptic vesicle and
mitochondrion membrane in a calmodulin-dependent manner (By
similarity). Localizes to the centrosome when phosphorylated at
Ser-49.

Bcl-X (S) is expressed at high levels in cells
that undergo a high rate of turnover, such as developing
lymphocytes. In contrast, Bcl-X (L) is found in tissues containing
long-lived postmitotic cells, such as adult brain.