Anti-MBP (phospho-T232) Antibody

Primary Antibodies

33117 MW

WB: 1:500-1:1000

Myelin basic protein

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

The classic group of MBP isoforms (isoform 4-isoform 14)
are with PLP the most abundant protein components of the myelin
membrane in the CNS. They have a role in both its formation and
stabilization. The smaller isoforms might have an important role
in remyelination of denuded axons in multiple sclerosis. The non-
classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may
preferentially have a role in the early developing brain long
before myelination, maybe as components of transcriptional
complexes, and may also be involved in signaling pathways in T-
cells and neural cells. Differential splicing events combined with
optional post-translational modifications give a wide spectrum of
isomers, with each of them potentially having a specialized
function. Induces T-cell proliferation.

Boster Bio Anti-MBP (phospho-T232) Antibody catalog # A00211T232. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.