Anti-c-Fos (phospho-T232) Antibody

Primary Antibodies

40695 MW

WB: 1:500-1:2000
IF 1:50-1:100

Proto-oncogene c-Fos

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Nuclear phosphoprotein which forms a tight but non-
covalently linked complex with the JUN/AP-1 transcription factor.
In the heterodimer, FOS and JUN/AP-1 basic regions each seems to
interact with symmetrical DNA half sites. On TGF-beta activation,
forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-
binding site to regulate TGF-beta-mediated signaling. Has a
critical function in regulating the development of cells destined
to form and maintain the skeleton. It is thought to have an
important role in signal transduction, cell proliferation and
differentiation. In growing cells, activates phospholipid
synthesis, possibly by activating CDS1 and PI4K2A. This activity
requires Tyr-dephosphorylation and association with the
endoplasmic reticulum.

Boster Bio Anti-c-Fos (phospho-T232) Antibody catalog # A00297T232. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.