Anti-Filamin 1 (phospho-S2152) FLNA Antibody

Primary Antibodies

280739 MW

WB: 1:500-1:1000
IHC: 1:50-1:200

Filamin-A

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Promotes orthogonal branching of actin filaments and
links actin filaments to membrane glycoproteins. Anchors various
transmembrane proteins to the actin cytoskeleton and serves as a
scaffold for a wide range of cytoplasmic signaling proteins.
Interaction with FLNA may allow neuroblast migration from the
ventricular zone into the cortical plate. Tethers cell surface-
localized furin, modulates its rate of internalization and directs
its intracellular trafficking (By similarity). Involved in
ciliogenesis. Plays a role in cell-cell contacts and adherens
junctions during the development of blood vessels, heart and brain
organs. Plays a role in platelets morphology through interaction
with SYK that regulates ITAM- and ITAM-like-containing receptor
signaling, resulting in by platelet cytoskeleton organization
maintenance (By similarity).

Boster Bio Anti-Filamin 1 (phospho-S2152) FLNA Antibody catalog # A00502S2152. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.