Anti-FasLG Antibody

ArtNr	BOS-A00925
Hersteller	Boster
Menge	100 ul
Kategorie	Cell Biology Cell Status Apoptosis Western Blot
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Tumor necrosis factor ligand superfamily member 6,Apoptosis antigen ligand,APTL,CD95 ligand,CD95-L,Fas antigen ligand,Fas ligand,FasL,CD178,Tumor necrosis factor ligand superfamily member 6,membrane form,Tumor necrosis factor ligand superfamily member 6,soluble form,Receptor-binding FasL ectodomain,Soluble Fas ligand,sFasL,ADAM10-processed FasL form,APL,FasL intracellular domain,FasL ICD,SPPL2A-processed FasL form,SPA,FASLG,APT1LG1,CD95L,FASL,TNFSF6
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	31485 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:2000
Gene Name	FASLG
Gene Full Name	Tumor necrosis factor ligand superfamily member 6
Immunogen	A synthetic peptide of human FASLG
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Tumor necrosis factor ligand superfamily member 6
Protein Function	Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:26334989, PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:9228058, PubMed:7528780, PubMed:9427603). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (By similarity). Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (PubMed:27806260).
Subcellular Localization	Cell membrane
Description	Boster Bio Anti-FasLG Antibody catalog # A00925. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Manufacturer - Alias	Tumor necrosis factor ligand superfamily member 6, Apoptosis antigen ligand, APTL, CD95 ligand, CD95-L, Fas antigen ligand, Fas ligand, FasL, CD178, Tumor necrosis factor ligand superfamily member 6, membrane form, Tumor necrosis factor ligand superfamily member 6, soluble form, Receptor-binding FasL ectodomain, Soluble Fas ligand, sFasL, ADAM10-processed FasL form, APL, FasL intracellular domain, FasL ICD, SPPL2A-processed FasL form, SPA, FASLG, APT1LG1, CD95L, FASL, TNFSF6

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BOS-A00925-datasheet.pdf

BOS-A00925-safety-datasheet.pdf