Anti-Rho B Antibody

Primary Antibodies

22123 MW

WB 1:500-2000
IHC 1:50-300
ELISA 1:2000-20000

Rho-related GTP-binding protein RhoB

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

1 mg/ml

Mediates apoptosis in neoplastically transformed cells
after DNA damage. Not essential for development but affects cell
adhesion and growth factor signaling in transformed cells. Plays a
negative role in tumorigenesis as deletion causes tumor formation.
Involved in intracellular protein trafficking of a number of
proteins. Targets PKN1 to endosomes and is involved in trafficking
of the EGF receptor from late endosomes to lysosomes. Also
required for stability and nuclear trafficking of AKT1/AKT which
promotes endothelial cell survival during vascular development.
Serves as a microtubule-dependent signal that is required for the
myosin contractile ring formation during cell cycle cytokinesis.
Required for genotoxic stress-induced cell death in breast cancer
cells.

Boster Bio Anti-Rho B Antibody catalog # A01550-2. Tested in WB, ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.