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Anti-Bim (phospho-S69/S65) BCL2L11 Antibody

Anti-Bim (phospho-S69/S65) BCL2L11 Antibody

ArtNr	BOS-A01552S69S65
Hersteller	Boster
Menge	100 ul
Kategorie	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Western Blot Autophagy
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Bcl-2-like protein 11,Bcl2-L-11,Bcl2-interacting mediator of cell death,BCL2L11,BIM
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	22171 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:1000
Gene Name	BCL2L11
Gene Full Name	Bcl-2-like protein 11
Immunogen	A synthetic peptide corresponding to residues in Human Bim around the phosphorylation site of Ser69.
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Bcl-2-like protein 11
Protein Function	Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
Subcellular Localization	Endomembrane system; Peripheral membrane protein. Associated with intracytoplasmic membranes.
Description	Boster Bio Anti-Bim (phospho-S69/S65) BCL2L11 Antibody catalog # A01552S69S65. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are widely expressed with tissue- specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-A01552S69S65-datasheet.pdf

BOS-A01552S69S65-safety-datasheet.pdf