Anti-PNPLA2 Antibody

ArtNr	BOS-A01800
Hersteller	Boster
Menge	100 ul
Kategorie	Metabolism Diabetes Cholesterol & Lipid Metabolism Western Blot Immunofluorescence Immunocytochemistry Enzymes Fatty Acid Catabolism Immunochemistry
Format	Liquid
Applikationen	WB, IF, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Patatin-like phospholipase domain-containing protein 2,3.1.1.3,Adipose triglyceride lipase,Calcium-independent phospholipase A2,Desnutrin,IPLA2-zeta,Pigment epithelium-derived factor,TTS2.2,Transport-secretion protein 2,TTS2,PNPLA2,ATGL,FP17548
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	55316 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:2000 ICC/IF: 1:50-1:200
Gene Name	PNPLA2
Gene Full Name	Patatin-like phospholipase domain-containing protein 2
Immunogen	Recombinant fusion protein of human PNPLA2(NP_065109.1).
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Patatin-like phospholipase domain-containing protein 2
Protein Function	Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674). Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes (PubMed:16239926). May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
Subcellular Localization	Lipid droplet. Cell membrane; Single-pass type II membrane protein.
Description	Boster Bio Anti-PNPLA2 Antibody catalog # A01800. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Highest expression in adipose tissue. Also detected in heart, skeletal muscle, and portions of the gastrointestinal tract. Detected in normal retina and retinoblastoma cells. Detected in retinal pigment epithelium and, at lower intensity, in the inner segments of photoreceptors and in the ganglion cell layer of the neural retina (at protein level).
Manufacturer - Alias	Patatin-like phospholipase domain-containing protein 2, 3.1.1.3, Adipose triglyceride lipase, Calcium-independent phospholipase A2, Desnutrin, IPLA2-zeta, Pigment epithelium-derived factor, TTS2.2, Transport-secretion protein 2, TTS2, PNPLA2, ATGL, FP17548

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BOS-A01800-datasheet.pdf

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