Anti-Sortilin-related receptor SORL1 Antibody

Primary Antibodies

248426 MW

WB: 1:500-1:2000

Sortilin-related receptor

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Likely to be a multifunctional endocytic receptor, that
may be implicated in the uptake of lipoproteins and of proteases.
Binds LDL, the major cholesterol-carrying lipoprotein of plasma,
and transports it into cells by endocytosis. Binds the receptor-
associated protein (RAP). Could play a role in cell-cell
interaction. Involved in APP trafficking to and from the Golgi
apparatus. It probably acts as a sorting receptor that protects
APP from trafficking to late endosome and from processing into
amyloid beta, thereby reducing the burden of amyloidogenic peptide
formation. Involved in the regulation of smooth muscle cells
migration, probably through PLAUR binding and decreased
internalization.

Boster Bio Anti-Sortilin-related receptor SORL1 Antibody catalog # A01887. Tested in WB applications. This antibody reacts with Human, Mouse.

Sortilin-related receptor, Low-density lipoprotein receptor relative with 11 ligand-binding repeats, LDLR relative with 11 ligand-binding repeats, LR11, SorLA-1, Sorting protein-related receptor containing LDLR class A repeats, SorLA, SORL1, C11orf32