Anti-VPS34 (phospho-Ser249) PIK3C3 Antibody

Primary Antibodies

101549 MW

WB: 1:500-1:1000

Phosphatidylinositol 3-kinase catalytic subunit type 3

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Catalytic subunit of the PI3K complex that mediates
formation of phosphatidylinositol 3-phosphate; different complex
forms are believed to play a role in multiple membrane trafficking
pathways: PI3KC3-C1 is involved in initiation of autophagosomes
and PI3KC3-C2 in maturation of autophagosomes and endocytosis.
Involved in regulation of degradative endocytic trafficking and
required for the abcission step in cytokinesis, probably in the
context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved
in the transport of lysosomal enzyme precursors to lysosomes.
Required for transport from early to late endosomes (By
similarity).

Boster Bio Anti-VPS34 (phospho-Ser249) PIK3C3 Antibody catalog # A02356S249. Tested in WB applications. This antibody reacts with Human.