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Anti-Intelectin-1 ITLN1 Antibody

Anti-Intelectin-1 ITLN1 Antibody

ArtNr	BOS-A02485
Hersteller	Boster
Menge	100 ul
Kategorie	Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Immunochemistry
Format	Liquid
Applikationen	WB, IF, IHC, ICC
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Intelectin-1,ITLN-1,Endothelial lectin HL-1,Galactofuranose-binding lectin,Intestinal lactoferrin receptor
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	34962 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:2000 IHC: 1:50-1:200 ICC/IF: 1:50-1:200
Gene Name	ITLN1
Gene Full Name	Intelectin-1
Immunogen	Recombinant fusion protein of human ITLN1(NP_060095.2).
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Intelectin-1
Protein Function	Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed:11313366, PubMed:26148048). Binds to microbial glycans that contain a terminal acyclic 1, 2-diol moiety, including beta- linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D- manno-oct-2-ulosonic acid (KDO) (PubMed:26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris (PubMed:26148048). Does not bind human glycans (PubMed:26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed:16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed:16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed:11747454, PubMed:23921499).
Subcellular Localization	Cell membrane
Description	Boster Bio Anti-Intelectin-1 ITLN1 Antibody catalog # A02485. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Mouse, Rat.
Tissue Specificity	Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level) (PubMed:16531507). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-A02485-datasheet.pdf

BOS-A02485-safety-datasheet.pdf