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Anti-AKR1B10 Antibody PicobandÂ®

Anti-AKR1B10 Antibody PicobandÂ®

ArtNr	BOS-A02976-Dylight550
Hersteller	Boster
Menge	100 ug
Format	Lyophilized
Applikationen	WB, IF, IHC, ICC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	1. Cao D, Fan ST, Chung SS (Jun 1998). "Identification and characterization of a novel human aldose reductase-like gene". J Biol Chem. 273 (19): 11429â€“35. 2. Hyndman DJ, Flynn TG (Oct 1998). "Sequence and expression levels in human tissues of a new member of the aldo-keto reductase family". Biochim Biophys Acta. 1399(2â€“3): 198â€“202.
Alias	Aldo-keto reductase family 1 member B10;1.1.1.-;ARL-1;Aldose reductase-like;Aldose reductase-related protein;ARP;hARP;Small intestine reductase;SI reductase;AKR1B10;AKR1B11;
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Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Conjugate / Tag	Dylight550
Storage Conditions	Store at -20Â°C for one year from date of receipt. After reconstitution, at 4Â°C for one month. It can also be aliquotted and stored frozen at -20Â°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	36 kDa
Calculated Molecular weight	36020 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5Î¼g/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1Î¼g/ml, Human, By Heat Immunocytochemistry/Immunofluorescence, 5 Î¼g/ml, Human
Manufacturer - Gene Name	AKR1B10
Gene Full Name	Aldo-keto reductase family 1 member B10
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Aldo-keto reductase family 1 member B10 is an enzyme that in humans is encoded by the AKR1B10 gene. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human AKR1B10.
Contents	Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 Î¼g/ml.
Manufacturer - Research Category	Cancer, Drug Metabolism, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Tumor Biomarkers
Protein Name	Aldo-keto reductase family 1 member B10
Protein Function	Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
Subcellular Localization	Lysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.
Description	Boster Bio Anti-AKR1B10 Antibody Picoband® catalog # A02976. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.

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Menge: 100 ug

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Lieferung vsl. bis 12.06.2025

Express-Lieferung: 10 Tage sparen

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