Anti-Glucagon Receptor (K136) GCGR Antibody

Primary Antibodies

54009 MW

WB: 1:500-1:1000
IF: 1:50-1:200

Glucagon receptor

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

G-protein coupled receptor for glucagon that plays a
central role in the regulation of blood glucose levels and glucose
homeostasis. Regulates the rate of hepatic glucose production by
promoting glycogen hydrolysis and gluconeogenesis. Plays an
important role in mediating the responses to fasting. Ligand
binding causes a conformation change that triggers signaling via
guanine nucleotide-binding proteins (G proteins) and modulates the
activity of down-stream effectors, such as adenylate cyclase.
Promotes activation of adenylate cyclase. Besides, plays a role in
signaling via a phosphatidylinositol-calcium second messenger
system.

Boster Bio Anti-Glucagon Receptor (K136) GCGR Antibody catalog # A03342. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.