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Anti-ZIP8 SLC39A8 Antibody

Anti-ZIP8 SLC39A8 Antibody

ArtNr	BOS-A04007
Hersteller	Boster
Menge	0.1 mg
Format	Liquid
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Alias	ZIP8, PP3105, BIGM103, LZT-Hs6, ZIP8, Zinc transporter ZIP8, BCG-induced integral membrane protein in monocyte clone 103 protein
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Manufacturer - Category	Primary Antibodies
Storage Conditions	ZIP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Observed Molecular Weight	49631 MW
Clonality	Polyclonal
Application Details	ZIP8 antibody can be used for detection of ZIP8 by Western blot at 1 - 2 ?g/mL. Antibody can also be used for immunohistochemistry starting at 5 ?g/mL. For immunofluorescence start at 20 ?g/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Manufacturer - Gene Name	SLC39A8
Gene Full Name	Solute carrier family 39 (zinc transporter), member 8
Background	The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.
Immunogen	ZIP8 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human ZIP8. The immunogen is located within the last 50 amino acids of ZIP8.
Contents	ZIP8 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification	ZIP8 Antibody is affinity chromatography purified via peptide column.
Concentration	1 mg/mL
Manufacturer - Research Category	Immunology
Protein Name	Solute carrier family 39 (zinc transporter), member 8
Protein Function	Acts as a manganese and zinc influx transporter (PubMed:12504855, PubMed:26637978). Plays a role in manganese reabsorption in the proximal tubule of the kidney and in manganese uptake into the brain (PubMed:26637978).
Subcellular Localization	Membrane; Multi-pass membrane protein. Associated with the lysosomal/endosomal compartment following transfection.
Short Description	Boster Bio Anti-ZIP8 SLC39A8 Antibody (Catalog # A04007). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Description	Boster Bio Anti-ZIP8 SLC39A8 Antibody (Catalog # A04007). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Tissue Specificity	Expressed in thymus, placenta, lung, liver, pancreas and, to a lower extent, in spleen, testis, ovary, small intestine, colon, leukocyte, heart. Highest expression is observed in pancreas.
Predicted Reactivity	Mouse, Rat

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Menge: 0.1 mg

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Lieferung vsl. bis 03.07.2025

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