Anti-KCNQ5 Antibody

Primary Antibodies

102179 MW

WB: 1:500-1:1000

Potassium voltage-gated channel subfamily KQT member 5

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Associates with KCNQ3 to form a potassium channel which
contributes to M-type current, a slowly activating and
deactivating potassium conductance which plays a critical role in
determining the subthreshold electrical excitability of neurons.
Therefore, it is important in the regulation of neuronal
excitability. May contribute, with other potassium channels, to
the molecular diversity of a heterogeneous population of M-
channels, varying in kinetic and pharmacological properties, which
underlie this physiologically important current. Insensitive to
tetraethylammonium, but inhibited by barium, linopirdine and
XE991. Activated by niflumic acid and the anticonvulsant
retigabine. As the native M-channel, the potassium channel
composed of KCNQ3 and KCNQ5 is also suppressed by activation of
the muscarinic acetylcholine receptor CHRM1.

Boster Bio Anti-KCNQ5 Antibody catalog # A04705. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.