Anti-ZBTB33 Antibody

ArtNr	BOS-A04754
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Targets for Rodent Neurosciences Immunoprecipitation Western Blot CHiP
Format	Liquid
Applikationen	WB, CHIP
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Transcriptional regulator Kaiso,Zinc finger and BTB domain-containing protein 33,ZBTB33,KAISO,ZNF348
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	74484 MW
Clonality	Polyclonal
Application Details	WB: 1:1000-1:2000 ChIP: 1:50-1:200
Gene Name	ZBTB33
Gene Full Name	Transcriptional regulator Kaiso
Immunogen	Recombinant fusion protein of human Kaiso/Kaiso/ZBTB33(NP_006768.1).
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Transcriptional regulator Kaiso
Protein Function	Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453).
Subcellular Localization	Nucleus
Description	Boster Bio Anti-ZBTB33 Antibody catalog # A04754. Tested in WB, ChIP applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in vascular endothelium.

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Arbeitsanleitung (Data Sheet) anfordern

BOS-A04754-datasheet.pdf

BOS-A04754-safety-datasheet.pdf