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Anti-Transcription factor HES-5 HES5 Antibody

Anti-Transcription factor HES-5 HES5 Antibody

ArtNr	BOS-A05384
Hersteller	Boster
Menge	0.1 mg
Format	Liquid
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Alias	Hairy and enhancer of split 5, hes family bHLH transcription factor 5, bHLHb38
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Manufacturer - Category	Primary Antibodies
Storage Conditions	HES5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Observed Molecular Weight	18226 MW
Clonality	Polyclonal
Application Details	HES5 antibody can be used for detection of HES5 by Western blot at 1 - 2 ?g/ml. Antibody can also be used for immunohistochemistry starting at 5 ?g/mL. For immunofluorescence start at 20 ?g/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Manufacturer - Gene Name	HES5
Gene Full Name	Hes family bHLH transcription factor
Background	HES5 is a member of the HES family of transcriptional repressors, which are the mammalian homologs of the Drosophila Hairy and Enhancer of Split and contain basic Helix-loop-helix (bHLH) and Orange domains (1). The HES5 gene is a downstream target of the Notch signaling pathway and its expression is downregulated during human cartilage differentiation (2). HES5 can directly repress transcription of the E3 ligase FBW7-beta, creating a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions (3).
Immunogen	HES5 antibody was raised against a 19 amino acid peptide near the amino terminus of human HES5. The immunogen is located within the first 50 amino acids of HES5.
Contents	HES5 antibody is supplied in PBS containing 0.02% sodium azide.
Purification	HES5 antibody is affinity chromatography purified via peptide column.
Concentration	1 mg/mL
Manufacturer - Research Category	Stem Cells
Protein Name	Hes family bHLH transcription factor
Protein Function	Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator (By similarity).
Subcellular Localization	Nucleus
Short Description	Boster Bio Anti-Transcription factor HES-5 HES5 Antibody (Catalog # A05384). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-Transcription factor HES-5 HES5 Antibody (Catalog # A05384). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in fetal heart and brain tumors.

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Menge: 0.1 mg

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Lieferung vsl. bis 03.07.2025

Express-Lieferung: 10 Tage sparen

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