Anti-USP44 Antibody

ArtNr	BOS-A08401
Hersteller	Boster
Menge	100 ul
Kategorie	Western Blot ELISA Immunostaining
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Alias	Ubiquitin carboxyl-terminal hydrolase 44,3.4.19.12,Deubiquitinating enzyme 44,Ubiquitin thioesterase 44,Ubiquitin-specific-processing protease 44,USP44
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	81185 MW
Application Details	WB 1:500-1:2000 ELISA 1:40000
Gene Name	USP44
Gene Full Name	Ubiquitin carboxyl-terminal hydrolase 44
Immunogen	The antiserum was produced against synthesized peptide derived from human USP44. AA range:211-260
Contents	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	Immunogen affinity purified
Concentration	1 mg/ml
Protein Function	Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B (H2BK120ub1) ubiquitination.
Subcellular Localization	Nucleus. Peaks in interphase, with relatively low levels maintained throughout mitosis.
Description	Boster Bio Anti-USP44 Antibody catalog # A08401. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Expressed in testis. Expressed at high levels in T-cell acute lymphoblastic leukemia.
Short Description	Boster Bio Anti-USP44 Antibody catalog # A08401. Tested in WB applications. This antibody reacts with Human.

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Arbeitsanleitung (Data Sheet) anfordern

BOS-A08401-datasheet.pdf

BOS-A08401-safety-datasheet.pdf