Anti-Phospho-GRK 2 (S29) Antibody

Primary Antibodies

79574 MW

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200

Beta-adrenergic receptor kinase 1

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

1 mg/ml

Specifically phosphorylates the agonist-occupied form of
the beta-adrenergic and closely related receptors, probably
inducing a desensitization of them. Key regulator of LPAR1
signaling. Competes with RALA for binding to LPAR1 thus affecting
the signaling properties of the receptor. Desensitizes LPAR1 and
LPAR2 in a phosphorylation-independent manner (PubMed:19306925,
PubMed:19715378). Positively regulates ciliary smoothened (SMO)-
dependent Hedgehog (Hh) signaling pathway by faciltating the
trafficking of SMO into the cilium and the stimulation of SMO
activity (By similarity).

Boster Bio Anti-Phospho-GRK 2 (S29) Antibody catalog # A32388S29. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Boster Bio Anti-Phospho-GRK 2 (S29) Antibody catalog # A32388S29. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.