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Anti-Ms CD90.2 Purified Azide Free Thy1 Monoclonal Antibody Europäischer Partner

ArtNr BOS-M01818-2
Hersteller Boster
Menge 0.1 mg
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, FC, ICC, FA
Clon 1aG4/C5
Specific against Mouse (Murine, Mus musculus)
Host Mouse
Isotype IgG3
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Thy-1.2
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at 2-8°C. Do not freeze.
Molecular Weight
18080 MW
Clonality
Monoclonal
Application Details
Functional application: The bound of antibody 1aG4/C5 to the transfected mast cells induces the activation processes which are similar, but not identical, to the antigen activation of IgE stimulated cells.
Immunoprecipitation: The antibody 1aG4/C5 precipitates complexes with Lyn protein tyrosine kinase.
Flow cytometry: 1 μg/ml.
Gene Name
THY1.2
Gene Full Name
Thy-1.2 cell surface antigen
Manufacturer - Specificity
This antibody does not cross-react with Thy-1.1 alloantigen.
Background
CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. In the mouse, CD90 is expressed mainly on thymocytes and peripheral T lymphocytes. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.
Immunogen
Thymocytes from C3H/Di mice (Thy-1.2 positive). The mouse monoclonal antibody 1aG4/C5 recognizes alloantigen Thy-1.2 of mouse Thy-1 (CD90). Thy-1 is an 18-35 kDa cell surface GPI anchored glycoprotein (immunoglobulin superfamily); in mouse it is abundant on thymocytes and peripheral T lymphocytes.
Contents
Phosphate buffered saline (PBS), pH 7.4, azide-free
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Protein Name
Thy-1 membrane glycoprotein
Protein Function
May play a role in cell-cell or cell-ligand interactions
during synaptogenesis and other events in the brain.
Subcellular Localization
Cell membrane; Lipid-anchor, GPI-anchor.
Description
Boster Bio Anti-Ms CD90.2 Purified Azide Free Thy1 Monoclonal Antibody (Catalog# M01818-2). Tested in Flow Cytometry, WB, ICC, Functional Assay application(s). This antibody reacts with Mouse.
Manufacturer - Cross Reactivity
This antibody does not cross-react with Thy-1.1 alloantigen.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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