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Anti-Fractalkine CX3CL1 Antibody Picoband® Europäischer Partner

ArtNr BOS-PA1400
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity <10pg/ml
Citations 1. Pan et al., Lloyd C, Zhou H, Dolich S, Deeds J, Gonzalo JA, Vath J, Gosselin M et al. (1997). "Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation". Nature 387 (6633): 611–617.
2. Bazan et al., Bacon KB, Hardiman G, Wang W, Soo K, Rossi D, Greaves DR, Zlotnik A et al. (1997). "A new class of membrane-bound chemokine with a CX3C motif". Nature 385 (6617): 640–644. doi:10.1038/385640a0. PMID 9024663.
3. Hannan, N. J., Jones, R. L., Critchley, H. O. D., Kovacs, G. J., Rogers, P. A. W., Affandi, B., Salamonsen, L. A.Coexpression of fractalkine and its receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role of fractalkine in leukocyte recruitment and endometrial remodeling.J. Clin. Endocr. Metab.89: 6119-6129, 2004.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Fractalkine;C-X3-C motif chemokine 1;CX3C membrane-anchored chemokine;Neurotactin;Small-inducible cytokine D1;Processed fractalkine;CX3CL1;FKN, NTT, SCYD1;A-152E5.2;
Similar products ABCD 3 antibody, ABCD3 antibody, A 152E5.2 antibody, AB030188 antibody, AI848747 antibody, C-X3-C motif chemokine 1 antibody, C3Xkine antibody, Chemokine(C-X3-C motif) ligand 1 antibody, Chemokine C X3 C motif ligand 1 antibody, Chemokine CX3C Motif Ligand 1 antibody, CX3C membrane anchored chemokine antibody, CX3C membrane-anchored chemokine antibody, CX3CL1 antibody, CXC 3 antibody, CXC3 antibody, CXC3C antibody, D8Bwg0439e antibody, FKN antibody, Fractalkine antibody, Neurotactin antibody, NTN antibody, NTT antibody, Processed fractalkine antibody, SCYD 1 antibody, SCYD1 antibody, Small inducible cytokine D1 antibody, Small inducible cytokine subfamily D(Cys X3 Cys) member 1 antibody, small inducible cytokine subfamily D(Cys-X3-Cys), member 1(fractalkine, neurotactin) antibody, Small inducible cytokine subfamily D member 1 antibody, Small-inducible cytokine D1 antibody, X3CL1_HUMAN antibody
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
90-100 kDa
Calculated Molecular weight
42203 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Human
Manufacturer - Gene Name
CX3CL1
Gene Full Name
Fractalkine
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Chemokine (C-X3-C motif) ligand 1, also known as CX3CL1, is a large cytokine protein. It is said to be the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice). Its gene is mapped to the long arm of chromosome 8. Being the large protein, it has got 373 amino acids. Imai et al. (1997) identified a 7-transmembrane high-affinity receptor (CX3CR1; 601470) for fractalkine and showed that it mediates both the adhesive and migratory functions of fractalkine.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human CX3CL1.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Atherosclerosis, Cardiovascular, Chemokines, Immunology, Innate Immunity, Macrophage/Inflammation, Vascular Inflammation
Protein Name
Fractalkine
Protein Function
The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
Subcellular Localization
Cell membrane; Single-pass type I membrane protein.
Description
Boster Bio Anti-Fractalkine CX3CL1 Antibody catalog # PA1400. Tested in WB applications. This antibody reacts with Human.
Tissue Specificity
Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
Sequence Similarities
Belongs to the intercrine delta family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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