Vergleich

Anti-IL3RA Antibody

Hersteller Boster
Kategorie
Typ Antibody Polyclonal
Specific against Human
Isotype IgG
Format Lyophilized
Applikationen WB
Menge 100 ug/vial
Host Rabbit
ArtNr BOS-PA1617
Targets IL3RA
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Manufacturers Product Category
Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category
Adapters, Cytokines, Immunology, Innate Immunity, Interleukins, Signal Transduction, Transmembrane
Short Description
Boster Bio Anti-IL3RA Antibody catalog # PA1617. Tested in WB applications. This antibody reacts with Human.
Description
Boster Bio Anti-IL3RA Antibody catalog # PA1617. Tested in WB applications. This antibody reacts with Human.
Background
IL3RA (INTERLEUKIN 3 RECEPTOR, ALPHA), also called CD123 (Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The IL3RA is mapped on Xp22.33. The genomic structures of IL3RA and CSF2RA are very similar and share an additional exon encoding part of the C-terminal domain not found in other members of this gene family. As in human hematopoietic cells, IL3 and GMCSF competed for binding in fibroblasts expressing the cDNAs for IL3RA, CSF2RA, and the common beta subunit, indicating that different alpha subunits compete for a common beta subunit.
Gene Name
IL3RA
Application Details
Western blot, 0.1-0.5μg/ml, Human
Application Notes
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality
Polyclonal
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human IL3RA.
Purification
Immunogen affinity purified.
Cross-reactivity
No cross-reactivity with other proteins
Storage
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name
Interleukin-3 receptor subunit alpha
Molecular Weight
43330 MW
Protein Function
This is a receptor for interleukin-3.
Subcellular Localization
Membrane; Single-pass type I membrane protein.
Protein Name
Interleukin-3 receptor subunit alpha(IL-3 receptor subunit alpha/IL-3R subunit alpha/IL-3R-alpha/IL-3RA)
Sequence Similarities
Belongs to the type I cytokine receptor family. Type 5 subfamily.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 13.06.2024 

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