Hersteller |
Boster
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human |
Isotype |
IgG |
Format |
Lyophilized |
Applikationen |
WB |
Menge |
100 ug/vial |
Host |
Rabbit |
ArtNr |
BOS-PA1617 |
Targets |
IL3RA |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Polyclonal Antibodies |
Manufacturers Research Category |
Adapters, Cytokines, Immunology, Innate Immunity, Interleukins, Signal Transduction, Transmembrane |
Short Description |
Boster Bio Anti-IL3RA Antibody catalog # PA1617. Tested in WB applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-IL3RA Antibody catalog # PA1617. Tested in WB applications. This antibody reacts with Human. |
Background |
IL3RA (INTERLEUKIN 3 RECEPTOR, ALPHA), also called CD123 (Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The IL3RA is mapped on Xp22.33. The genomic structures of IL3RA and CSF2RA are very similar and share an additional exon encoding part of the C-terminal domain not found in other members of this gene family. As in human hematopoietic cells, IL3 and GMCSF competed for binding in fibroblasts expressing the cDNAs for IL3RA, CSF2RA, and the common beta subunit, indicating that different alpha subunits compete for a common beta subunit. |
Gene Name |
IL3RA |
Application Details |
Western blot, 0.1-0.5μg/ml, Human |
Application Notes |
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. |
Clonality |
Polyclonal |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Immunogen |
A synthetic peptide corresponding to a sequence in the middle region of human IL3RA. |
Purification |
Immunogen affinity purified. |
Cross-reactivity |
No cross-reactivity with other proteins |
Storage |
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles. |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Gene Full Name |
Interleukin-3 receptor subunit alpha |
Molecular Weight |
43330 MW |
Protein Function |
This is a receptor for interleukin-3. |
Subcellular Localization |
Membrane; Single-pass type I membrane protein. |
Protein Name |
Interleukin-3 receptor subunit alpha(IL-3 receptor subunit alpha/IL-3R subunit alpha/IL-3R-alpha/IL-3RA) |
Sequence Similarities |
Belongs to the type I cytokine receptor family. Type 5 subfamily. |
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