Anti-CD41/Integrin alpha 2b/ITGA2B Antibody

ArtNr	BOS-A01102
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Food Safety Proteins Neuroscience Neural Adhesion Molecules Antibodies Flow Cytometry Immunohistochemistry ELISA Primary Antibodies By Organ Skin Cancer
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	FC, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	1. "Entrez Gene: ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)". 2. Naik UP, Parise LV (1997). "Structure and function of platelet alpha IIb beta 3.". Curr. Opin. Hematol. 4(5): 317–22. 3. Quinn MJ, Byzova TV, Qin J et al. (2004). "Integrin alphaIIbbeta3 and its antagonism.". Arterioscler. Thromb. Vasc. Biol. 23 (6): 945–52.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Specificity	No cross reactivity with other proteins.
Storage Conditions	At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time. Avoid repeated freezing and thawing.
Manufacturer - Gene Name	ITGA2B
Gene Full Name	interleukin 23 subunit alpha
Background	Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. It is mapped to 17q21.32. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Immunogen	E. coli-derived human ITGA2B recombinant protein (Position: L32-D263).
Contents	Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Protein Name	Integrin alpha-Iib

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BOS-A01102-datasheet.pdf

BOS-A01102-safety-datasheet.pdf