Anti-MMP2 Antibody

ArtNr	BOS-PA1122-2
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies By Cell Type Blastoma Cell Biology Cell Stainings ECM Cardiovascular Research Atherosclerosis Primary Antibodies
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Nagase, H.; Barrett, A. J.; Woessner, J. F., Jr. : Nomenclature and glossary of the matrix metalloproteinases. Matrix Suppl. 1: 421-424, 1992. 2. Collier, I. E.; Bruns, G. A. P.; Goldberg, G. I.; Gerhard, D. S. : On the structure and chromosome location of the 72- and 92-kDa human type IV collagenase genes. Genomics 9: 429-434, 1991. 3. Huhtala, P.; Chow, L. T.; Tryggvason, K. : Structure of the human type IV collagenase gene. J. Biol. Chem. 265: 11077-11082, 1990. 4. Irwin, J. C.; Kirk, D.; Gwatkin, R. B. L.; Navre, M.; Cannon, P.; Giudice, L. C. : Human endometrial matrix metalloproteinase-2, a putative menstrual proteinase: hormonal regulation in cultured stromal cells and messenger RNA expression during the menstrual cycle. J. Clin. Invest. 97: 438-447, 1996.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	72 kDa gelatinase antibody, 72kD type IV collagenase antibody, CLG 4 antibody, CLG 4A antibody, CLG4 antibody, CLG4A antibody, Collagenase Type 4 alpha antibody, Collagenase type IV A antibody, Gelatinase A antibody, Gelatinase alpha antibody, Gelatinase neutrophil antibody, Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase antibody, Matrix metalloproteinase 2(gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) antibody, Matrix Metalloproteinase 2 antibody, Matrix metalloproteinase II antibody, Matrix metalloproteinase-2 antibody, MMP 2 antibody, MMP II antibody, MMP-2 antibody, MMP2 antibody, MMP2_HUMAN antibody, MONA antibody, Neutrophil gelatinase antibody, PEX antibody, TBE 1 antibody, TBE-1 antibody
Similar products	72kDa gelatinase, 72 kDa gelatinase antibody, 72kD type IV collagenase antibody, CLG 4 antibody, CLG 4A antibody, CLG4 antibody, CLG4A antibody, Collagenase Type 4 alpha antibody, Collagenase type IV A antibody, Gelatinase A antibody, Gelatinase alpha antibody, Gelatinase neutrophil antibody, Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase antibody, Matrix metalloproteinase 2(gelatinase A, 72kDa type IV collagenase) antibody, Matrix Metalloproteinase 2 antibody, Matrix metalloproteinase II antibody, Matrix metalloproteinase-2 antibody, MMP 2 antibody, MMP II antibody, MMP-2 antibody, MMP2 antibody, MMP2_HUMAN antibody, MONA antibody, Neutrophil gelatinase antibody, PEX antibody, TBE 1 antibody, TBE-1 antibody
Lieferbar
Specificity	No cross reactivity with other proteins.
Storage Conditions	At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time. Avoid repeated freezing and thawing.
Manufacturer - Gene Name	MMP2
Gene Full Name	matrix metallopeptidase 2(gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
Background	Matrix metalloproteinase-2(MMP2) is a Type IV collagenase, 72-kD, which is also known as gelatinase and is a member of a group of secreted zinc metalloproteases. The MMP2 gene is 17 kb long with 13 exons varying in size from 110 to 901 bp and 12 introns ranging from 175 to 4, 350 bp, located within a region of human chromosome 16q13. In addition, the extra exons encode the amino acids of the fibronectin-like domain which has so far been found in only the 72- and 92-kDa type IV collagenase. MMP2, which has a critical role in the binding of progelatinase A and TIMP4 via the C-terminal hemopexin-like domain(C domain), is functionally associated on the surface of angiogenic blood vessels. NOT only is a likely effector of endometrial menstrual breakdown, MMP2 is also effector and regulator of the inflammatory response. Moreover, MMP2 could be helpful in diagnosing Takayasu arteritis.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human MMP2(138-153aa ETVDDAFARAFQVWSD), different from the related rat and mouse sequences by two amino acids.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Protein Name	72 kDa type IV collagenase

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