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Anti-Galactoside 2-alpha-L-fucosyltransferase 1/FUT1 Antibody Picoband™

Anti-Galactoside 2-alpha-L-fucosyltransferase 1/FUT1 Antibody Picoband™

Hersteller	Boster
Kategorie	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Format	Lyophilized
Applikationen	WB, IHC
Menge	100 ug/vial
Host	Rabbit
ArtNr	BOS-PB9593
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Golgi Proteins, Protein Trafficking, Signal Transduction
Short Description	Boster Bio Anti-Galactoside 2-alpha-L-fucosyltransferase 1/FUT1 Antibody Picoband™ catalog # PB9593. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-Galactoside 2-alpha-L-fucosyltransferase 1/FUT1 Antibody Picoband™ catalog # PB9593. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Background	Galactoside 2-alpha-L-fucosyltransferase 1 is an enzyme that in humans is encoded by the FUT1 gene. It is mapped to 19q13.3. The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.
Gene Name	FUT1
Application Details	Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat Western blot, 0.1-0.5μg/ml, Human, Rat
Application Notes	Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human FUT1, different from the related mouse and rat sequences by seven amino acids.
Purification	Immunogen affinity purified.
Cross-reactivity	No cross-reactivity with other proteins
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	Galactoside 2-alpha-L-fucosyltransferase 1
Molecular Weight	41251 MW
Protein Function	Creates a soluble precursor oligosaccharide FuC-alpha ( (1, 2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values.
Subcellular Localization	Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Membrane-bound form in trans cisternae of Golgi.
Protein Name	Galactoside 2-alpha-L-fucosyltransferase 1
Sequence Similarities	Belongs to the glycosyltransferase 11 family.

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