Anti-CD44 Antibody

ArtNr	BOS-PA1021-1
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Carcinoma Hematology Myeloma Melanoma Cell Biology Cell Movement Cell Adhesion Primary Antibodies By Organ Bladder Cancer Colorectal Cancer Breast Cancer Head & Neck Cancer Heart & Blood Cancer Testicular & Prostate Cancer Gastric Cancer
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	IHC, ICC
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Screaton GR, Bell MV, Jackson DG, Cornelis FB, Gerth U, Bell JI. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):12160-4. 2. Telen MJ, Udani M, Washington MK, Levesque MC, Lloyd E, Rao N. A blood group-related polymorphism of CD44 abolishes a hyaluronan-binding consensus sequence without preventing hyaluronan binding. J Biol Chem. 1996 Mar 22; 271(12):7147-53. 3. Weber GF, Ashkar S, Glimcher MJ, Cantor H. Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science. 1996 Jan 26; 271(5248):509-12. 4. Sherman L, Wainwright D, Ponta H, Herrlich P. A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth. Genes Dev. 1998 Apr 1; 12(7):1058-71. 5. van Royen N, Voskuil M, Hoefer I, Jost M, de Graaf S, Hedwig F, Andert JP, Wormhoudt TA, Hua J, Hartmann S, Bode C, Buschmann I, Schaper W, van der Neut R, Piek JJ, Pals ST.CD44 regulates arteriogenesis in mice and is differentially expressed in patients with poor and good collateralization. Circulation. 2004 Apr 6; 109(13):1647-52.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	LHR antibody, BA-1 antibody, CD 44 antibody, CD44 antibody, CD44 antigen antibody, CD44 molecule(Indian blood group) antibody, CD44 molecule antibody, CD44_HUMAN antibody, CDw44 antibody, Cell surface glycoprotein CD44 antibody, chondroitin sulfate proteoglycan 8 antibody, CSPG8 antibody, ECMR-III antibody, Epican antibody, Extracellular matrix receptor III antibody, GP90 lymphocyte homing/adhesion receptor antibody, HCELL antibody, hematopoietic cell E- and L-selectin ligand antibody, Heparan sulfate proteoglycan antibody, Hermes antigen antibody, homing function and Indian blood group system antibody, HSA antibody, HUTCH-I antibody, HUTCH1 antibody, Hyaluronate receptor antibody, IN antibody, LHR antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MGC10468 antibody, MIC4 antibody, MUTCH1 antibody, PGP-1 antibody, PGP-I antibody, PGP1 antibody, Phagocytic glycoprotein 1 antibody, Phagocytic glycoprotein I antibody
Similar products	LHR antibody, BA-1 antibody, CD 44 antibody, CD44 antibody, CD44 antigen antibody, CD44 molecule(Indian blood group) antibody, CD44 molecule antibody, CD44_HUMAN antibody, CDw44 antibody, Cell surface glycoprotein CD44 antibody, chondroitin sulfate proteoglycan 8 antibody, CSPG8 antibody, ECMR-III antibody, Epican antibody, Extracellular matrix receptor III antibody, GP90 lymphocyte homing/adhesion receptor antibody, HCELL antibody, hematopoietic cell E- and L-selectin ligand antibody, Heparan sulfate proteoglycan antibody, Hermes antigen antibody, homing function and Indian blood group system antibody, HSA antibody, HUTCH-I antibody, HUTCH1 antibody, Hyaluronate receptor antibody, IN antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MGC10468 antibody, MIC4 antibody, MUTCH1 antibody, PGP-1 antibody, PGP-I antibody, PGP1 antibody
Lieferbar
Specificity	No cross reactivity with other proteins.
Storage Conditions	At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time. Avoid repeated freezing and thawing.
Manufacturer - Gene Name	CD44
Gene Full Name	CD40 ligand
Background	The CD44 gene, which is a transmembrane protein, is expressed as a family of molecular isoforms generated from alternative RNA splicing and posttranslational modifications. The gene, which contains 19 exons spanning some 50 kb of genomic DNA, is a widely expressed integral membrane protein that acts as a receptor for hyaluronan(HA) and is important to cell-extracellular matrix interaction. CD44 binding with HA can play an important role in cellular aggregation and tumor cell growth. CD44 is necessary for limb development and functions in a novel growth factor presentation mechanism. A specific CD44 splice variant is crucial for the proliferation of these mesenchymal cells. CD44 glycoproteins are involved in leukocyte extravasation but also in the regulation of growth factor activation, stability, and signaling. Moreover, it plays a pivotal role in arteriogenesis.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human CD44(63-82aa MAQMEKALSIGFETCRYGFI), different from the related rat sequence by three amino acids.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Protein Name	CD44 antigen

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