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Anti-Interleukin-3 IL3 Antibody Picoband® Europäischer Partner

ArtNr BOS-PA1728
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Sensitivity <10pg/ml
Citations 1. Le Beau, M. M.; Epstein, N. D.; O'Brien, S. J.; Nienhuis, A. W.; Yang, Y.-C.; Clark, S. C.; Rowley, J. D. The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q. Proc. Nat. Acad. Sci. 84: 5913-5917, 1987.
2. Clark-Lewis, I.; Aebersold, R.; Ziltener, H.; Schrader, J. W.; Hood, L. E.; Kent, S. B. H. Automated chemical synthesis of a protein growth factor for hemopoietic cells, interleukin-3. Science 231: 134-139, 1986.
3. Fung, M. C.; Hapel, A. J.; Ymer, S.; Cohen, D. R.; Johnson, R. M.; Campbell, H. D.; Young, I. G. Molecular cloning of cDNA for murine interleukin-3. Nature 307: 233-237, 1984.
4. Ihle, J. N.; Silver, J.; Kozak, C. A. Genetic mapping of the mouse interleukin 3 gene to chromosome 11. J. Immun. 138: 3051-3054, 1987.
5. Yang, Y.-C.; Kovacic, S.; Kriz, R.; Wolf, S.; Clark, S. C.; Wellems, T. E.; Nienhuis, A.; Epstein, N. The human genes for GM-CSF and IL3 are closely linked in tandem on chromosome 5. Blood 71: 958-961, 1988.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Interleukin-3;IL-3;Hematopoietic growth factor;Mast cell growth factor;MCGF;Multipotential colony-stimulating factor;P-cell-stimulating factor;Il3;Csfmu, Il-3;
Similar products Colony stimulating factor multiple antibody, Hematopoietic growth factor antibody, IL 3 antibody, IL-3 antibody, IL3 antibody, Interleukin 3(colony stimulating factor, multiple) antibody, Interleukin 3 antibody, Interleukin-3 antibody, Mast cell growth factor antibody, MCGF antibody, MGC79398 antibody, MGC79399 antibody, Multi CSF antibody, Multilineage colony stimulating factor antibody, Multipotential colony stimulating factor antibody, Multipotential colony-stimulating factor antibody, OTTHUMP00000065963 antibody, P cell stimulating factor antibody, P-cell-stimulating factor antibody, IL3_HUMAN antibody
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
14 kDa
Calculated Molecular weight
18540 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Mouse
Manufacturer - Gene Name
IL3
Gene Full Name
Interleukin-3
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Interleukin 3, also known as IL-3, is a protein that in humans is encoded by the IL3 gene. Ot is mapped to 5q31.1. IL-3 is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the interleukin-3 receptor. IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells or, with the addition of IL-7, into lymphoid progenitor cells. In addition, IL-3 stimulates proliferation of all cells in the myeloid lineage (granulocytes, monocytes, and dendritic cells), in conjunction with other cytokines, e.g., Erythropoietin (EPO), Granulocyte macrophage colony-stimulating factor (GM-CSF), and IL-6. IL-3 is secreted by basophils and activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of mouse IL-3.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cytokines, Immunology, Innate Immunity, Interleukins
Protein Name
Interleukin-3(IL-3)
Protein Function
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-Interleukin-3 IL3 Antibody catalog # PA1728. Tested in WB applications. This antibody reacts with Mouse.
Tissue Specificity
Activated T-cells, mast cells, natural killer cells.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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