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Anti-Prealbumin/TTR Antibody Picoband™

Anti-Prealbumin/TTR Antibody Picoband™

Hersteller	Boster
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Thyroid Cancer
Typ	Antibody Polyclonal
Specific against	Mouse, Rat
Isotype	IgG
Format	Lyophilized
Applikationen	WB, IF, IHC
Menge	100 ug/vial
Host	Rabbit
ArtNr	BOS-PB9750
Targets	TTR
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Alzheimer's Disease, Cardiovascular, Neurodegenerative Disease, Neurology Process, Neuroscience, Serum Proteins
Short Description	Boster Bio Anti-Prealbumin/TTR Antibody Picoband™ catalog # PB9750. Tested in IF, IHC, WB applications. This antibody reacts with Mouse, Rat.
Description	Boster Bio Anti-Prealbumin/TTR Antibody Picoband™ catalog # PB9750. Tested in IF, IHC, WB applications. This antibody reacts with Mouse, Rat.
Background	Transthyretin (TTR) is also known as prealbumin. It is mapped to chromosome region 18q11.2-q12.1. This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol. The protein consists of a tetramer of identical subunits. Due to increased stability of the tetramer form of this encoded protein in mouse, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils. In humans, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease.
Gene Name	TTR
Application Details	Western blot, 0.1-0.5μg/ml, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, By Heat Immunofluorescence, 5 μg/ml, Mouse, Rat
Application Notes	Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen	E.coli-derived rat Prealbumin recombinant protein (Position: G21-N147). Rat Prealbumin shares 94.5% amino acid (aa) sequence identity with mouse Prealbumin.
Purification	Immunogen affinity purified.
Cross-reactivity	No cross-reactivity with other proteins.
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	Transthyretin
Molecular Weight	15720 MW
Protein Function	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain..
Subcellular Localization	Secreted.
Tissue Specificity	Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in the choroid plexus. Detected at lower levels in the liver..
Protein Name	Transthyretin

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