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Anti-eIF4B(Ab-422) Antibody

Anti-eIF4B(Ab-422) Antibody

ArtNr	BOS-A00846
Hersteller	Boster
Menge	100 ul
Kategorie	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Eukaryotic translation initiation factor 4B;eIF-4B;EIF4B;
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	69151 MW
Clonality	Polyclonal
Application Details	Predicted MW: 80kd Western blotting: 1:500~1:1000 Immunohistochemistry: 1:50~1:100
Manufacturer - Gene Name	EIF4B
Gene Full Name	Eukaryotic translation initiation factor 4B
Background	Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. Gingras, A.C. et al. (2001) Genes Dev. 15, 807-826. Duncan, R. and Hershey, J.W. (1985) J. Biol. Chem. 260, 5493-5497. Duncan, R.F. and Hershey, J.W. (1989) J. Cell Biol. 109, 1467-1481.
Immunogen	Peptide sequence around aa.420~424 (T-G-S-E-S) derived from Human eIF4B.
Contents	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration	1 mg/ml
Manufacturer - Research Category	DNA/RNA, Epigenetics and Nuclear Signaling, Translation
Protein Function	Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Short Description	Boster Bio Anti-eIF4B(Ab-422) Antibody (Catalog # A00846). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-eIF4B(Ab-422) Antibody (Catalog # A00846). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

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BOS-A00846-datasheet.pdf

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