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Anti-HtrA2/Omi Antibody

Anti-HtrA2/Omi Antibody

ArtNr	BOS-A01941-1
Hersteller	Boster
Menge	100 ul
Kategorie	Food Safety Allergenes Neuroscience Neuroinflammation Neural Mitochondrial Function Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HTRA2;OMI;PRSS25;Serine protease HTRA2; mitochondrial;High temperature requirement protein A2;HtrA2;Omi stress-regulated endoprotease;Serine protease 25;Serine proteinase OMI
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Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	48841 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry, 1:100 - 1:300 ELISA, 1:40000 Not yet tested in other applications.
Manufacturer - Gene Name	HTRA2
Gene Full Name	Serine protease HTRA2, mitochondrial
Immunogen	A peptide derived from human HtrA2. Immunogen sequence location: 181-230
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Apoptosis, Cancer, Cell Biology, Cell Death, Invasion/Microenvironment, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Neurodegenerative Disease, Neurology Process, Neuroscience, Oxidative Stress, Pathways and Processes, Redox Metabolism
Protein Function	Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
Subcellular Localization	Mitochondrion intermembrane space. Mitochondrion membrane; Single-pass membrane protein. Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.
Short Description	Boster Bio Anti-HtrA2/Omi Antibody (Catalog# A01941-1). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-HtrA2/Omi Antibody (Catalog# A01941-1). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Isoform 1 is ubiquitous.Isoform 2 is expressed predominantly in the kidney, colon and thyroid.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-A01941-1-datasheet.pdf

BOS-A01941-1-safety-datasheet.pdf