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Anti-HtrA2/Omi Antibody

Anti-HtrA2/Omi Antibody

Hersteller	Boster
Kategorie	Food Safety Allergenes Neuroscience Neuroinflammation Neural Mitochondrial Function Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Primary Antibodies
Typ	Antibody
Specific against	Human, Mouse, Rat
Isotype	IgG
Format	Liquid
Applikationen	IF, ELISA, IHC-P
Menge	100ul
Host	Rabbit
ArtNr	BOS-A01941-1
Targets	HTRA2
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Manufacturers Product Category	Primary Antibodies
Manufacturers Research Category	Apoptosis, Cancer, Cell Biology, Cell Death, Invasion/Microenvironment, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Neurodegenerative Disease, Neurology Process, Neuroscience, Oxidative Stress, Pathways and Processes, Redox Metabolism
Short Description	Boster Bio Anti-HtrA2/Omi Antibody (Catalog# A01941-1). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-HtrA2/Omi Antibody (Catalog# A01941-1). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Gene Name	HTRA2
Clonality	Polyclonal
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Application Details	Immunohistochemistry, 1:100 - 1:300 ELISA, 1:40000 Not yet tested in other applications.
Immunogen	A peptide derived from human HtrA2. Immunogen sequence location: 181-230
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Storage	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Serine protease HTRA2, mitochondrial
Molecular Weight	48841 MW
Protein Function	Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
Subcellular Localization	Mitochondrion intermembrane space. Mitochondrion membrane; Single-pass membrane protein. Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.
Tissue Specificity	Isoform 1 is ubiquitous.Isoform 2 is expressed predominantly in the kidney, colon and thyroid.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100ul

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Lieferung vsl. bis 16.05.2024

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