Anti-PTPN13/PTPL1 (FAP1) Antibody

ArtNr	BOS-A02481
Hersteller	Boster
Menge	50 ul
Kategorie	Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB, IP, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tyrosine-protein phosphatase non-receptor type 13;3.1.3.48;Fas-associated protein-tyrosine phosphatase 1;FAP-1;PTP-BAS;Protein-tyrosine phosphatase 1E;PTP-E1;hPTPE1;Protein-tyrosine phosphatase PTPL1;PTPN13;PNP1, PTP1E, PTPL1;
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Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Observed Molecular Weight	276906 MW
Clonality	Polyclonal
Application Details	WB: 1:1000-1:2000 IHC (paraffin): 1:1000-1:5000 IHC (frozen): Users should optimize IP: 1:50-1:200
Manufacturer - Gene Name	PTPN13
Gene Full Name	Tyrosine-protein phosphatase non-receptor type 13
Immunogen	A recombinant protein of human FAP-1 (amino acids 1279 to 1883)
Contents	50 μ l sera
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cancer, Cell Biology, Cell Cycle, Kinases/Phosphatases, Protein Phosphorylation, Signal Transduction, Tyrosine Phosphatases
Protein Name	Tyrosine-protein phosphatase non-receptor type 13
Protein Function	Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317).
Subcellular Localization	Cytoplasm, cytoskeleton. Nucleus. Cell projection, lamellipodium. Colocalizes with PKN2 in lamellipodia-like structure, regions of large actin turnover.
Short Description	Boster Bio Anti-PTPN13/PTPL1 (FAP1) Antibody (Catalog# A02481). Tested in IP, IHC, WB application(s). This antibody reacts with Human.
Description	Boster Bio Anti-PTPN13/PTPL1 (FAP1) Antibody (Catalog# A02481). Tested in IP, IHC, WB application(s). This antibody reacts with Human.
Tissue Specificity	Present in most tissues with the exception of the liver and skeletal muscle. Most abundant in lung, kidney and fetal brain.

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BOS-A02481-datasheet.pdf

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