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Anti-ARHGEF7/Beta Pix Antibody

Anti-ARHGEF7/Beta Pix Antibody

ArtNr	BOS-A02764
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Signaling Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Rho Subfamily
Typ	Antibody
Format	Liquid
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ARHGEF7;COOL1;KIAA0142;P85SPR;PAK3BP;PIXB;Nbla10314;Rho guanine nucleotide exchange factor 7;Beta-Pix;COOL-1;PAK-interacting exchange factor beta;p85
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Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	90012 MW
Clonality	Polyclonal
Application Details	Western Blot, 1:500 - 1:2000 Immunohistochemistry, 1:100 - 1:300 ELISA, 1:5000 Not yet tested in other applications.
Manufacturer - Gene Name	ARHGEF7
Gene Full Name	Rho guanine nucleotide exchange factor 7
Immunogen	A peptide derived from human ARHGEF7. Immunogen sequence location: 311 - 360
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Actin, etc., Cancer, Cytoskeleton, Cytoskeleton/ECM, G Protein Signaling, Microfilaments, Signal Transduction, Signaling Pathway, Small G Proteins
Protein Function	Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Subcellular Localization	Cell junction, focal adhesion. Cell projection, ruffle. Cytoplasm, cell cortex. Cell projection, lamellipodium. Detected at cell adhesions. A small proportion is detected at focal adhesions.
Short Description	Boster Bio Anti-ARHGEF7/Beta Pix Antibody (Catalog# A02764). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-ARHGEF7/Beta Pix Antibody (Catalog# A02764). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-A02764-datasheet.pdf

BOS-A02764-safety-datasheet.pdf