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Anti-CDK5RAP2 Antibody

Anti-CDK5RAP2 Antibody

ArtNr	BOS-A03102
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Neural Signaling Antibodies Immunohistochemistry Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CDK5RAP2;CEP215;KIAA1633;CDK5 regulatory subunit-associated protein 2;CDK5 activator-binding protein C48;Centrosome-associated protein 215
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	215038 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry, 1:100 - 1:300 ELISA, 1:20000 Not yet tested in other applications.
Manufacturer - Gene Name	CDK5RAP2
Gene Full Name	CDK5 regulatory subunit-associated protein 2
Immunogen	A peptide derived from human CDK5RAP2. Immunogen sequence location: 251-300
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cell Biology, Cell Cycle, Chromosome Structure, Cytoskeleton, Cytoskeleton/ECM, Epigenetics and Nuclear Signaling, Kinases/Phosphatases, Microtubules, Neurogenesis, Neurology Process, Neuroscience, Organelles, Signal Transduction, Subcellular Markers, Tags & Cell Markers, Tubulin
Protein Function	Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with MAPRE1, it may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of a gamma- tubulin ring complex onto centrosomes (PubMed:26485573).
Subcellular Localization	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Golgi apparatus.Cytoplasm. Found in the pericentriolar region adhering to the surface of the centrosome and in the region of the centrosomal appendages. Localizes to microtubule plus ends.
Short Description	Boster Bio Anti-CDK5RAP2 Antibody (Catalog# A03102). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.
Description	Boster Bio Anti-CDK5RAP2 Antibody (Catalog# A03102). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.
Tissue Specificity	Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-A03102-datasheet.pdf

BOS-A03102-safety-datasheet.pdf